S-Adenosyl-l-methionine Modulates CO and NO(•) Binding to the Human H(2)S-generating Enzyme Cystathionine β-Synthase

Cystathionine β-synthase (CBS) is a key enzyme in human (patho)physiology with a central role in hydrogen sulfide metabolism. The enzyme is composed of a pyridoxal 5′-phosphate-binding catalytic domain, flanked by the following two domains: a heme-binding N-terminal domain and a regulatory C-termina...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Vicente, João B., Colaço, Henrique G., Sarti, Paolo, Leandro, Paula, Giuffrè, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Enzymology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705378/
https://ncbi.nlm.nih.gov/pubmed/26582199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.681221
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