Propranolol Targets Hemangioma Stem Cells via cAMP and Mitogen-Activated Protein Kinase Regulation

Infantile hemangiomas (IHs) are the most common vascular tumor and arise from a hemangioma stem cell (HemSC). Propranolol has proved efficacious for problematic IHs. Propranolol is a nonselective β-adrenergic receptor (βAR) antagonist that can lower cAMP levels and activate the mitogen-activated pro...

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Detaylı Bibliyografya
Yayımlandı:Stem Cells Transl Med
Asıl Yazarlar: Munabi, Naikhoba C.O., England, Ryan W., Edwards, Andrew K., Kitajewski, Alison A., Tan, Qian Kun, Weinstein, Andrew, Kung, Justin E., Wilcox, Maya, Kitajewski, Jan K., Shawber, Carrie J., Wu, June K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: AlphaMed Press 2016
Konular:
Tissue-Specific Progenitor and Stem Cells
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704871/
https://ncbi.nlm.nih.gov/pubmed/26574555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2015-0076
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