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Propranolol Accelerates Adipogenesis in Hemangioma Stem Cells and Causes Apoptosis of Hemangioma Endothelial Cells

BACKGROUND: Infantile hemangiomas (IHs) can cause significant morbidity during proliferation, yet there is no FDA-approved treatment. IHs are believed to form from stem cells (HemSCs), which differentiate towards an endothelial cell (HemECs) phenotype. Recently, propranolol has demonstrated effectiv...

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Detalhes bibliográficos
Main Authors: Wong, Alvin, Hardy, Krista L., Kitajewski, Alex M., Shawber, Carrie J., Kitajewski, Jan K., Wu, June K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668332/
https://ncbi.nlm.nih.gov/pubmed/23096601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PRS.0b013e318267d3db
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