NOTCH3 regulates stem-to–mural cell differentiation in infantile hemangioma

Infantile hemangioma (IH) is a vascular tumor that begins with rapid vascular proliferation shortly after birth, followed by vascular involution in early childhood. We have found that NOTCH3, a critical regulator of mural cell differentiation and maturation, is expressed in hemangioma stem cells (He...

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Bibliographic Details
Published in:JCI Insight
Main Authors: Edwards, Andrew K., Glithero, Kyle, Grzesik, Peter, Kitajewski, Alison A., Munabi, Naikhoba C.O., Hardy, Krista, Tan, Qian Kun, Schonning, Michael, Kangsamaksin, Thaned, Kitajewski, Jan K., Shawber, Carrie J., Wu, June K.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2017
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752265/
https://ncbi.nlm.nih.gov/pubmed/29093274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.93764
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