NOTCH3 regulates stem-to–mural cell differentiation in infantile hemangioma

Infantile hemangioma (IH) is a vascular tumor that begins with rapid vascular proliferation shortly after birth, followed by vascular involution in early childhood. We have found that NOTCH3, a critical regulator of mural cell differentiation and maturation, is expressed in hemangioma stem cells (He...

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Publicat a:JCI Insight
Autors principals: Edwards, Andrew K., Glithero, Kyle, Grzesik, Peter, Kitajewski, Alison A., Munabi, Naikhoba C.O., Hardy, Krista, Tan, Qian Kun, Schonning, Michael, Kangsamaksin, Thaned, Kitajewski, Jan K., Shawber, Carrie J., Wu, June K.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752265/
https://ncbi.nlm.nih.gov/pubmed/29093274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.93764
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