NOTCH3 regulates stem-to–mural cell differentiation in infantile hemangioma

Infantile hemangioma (IH) is a vascular tumor that begins with rapid vascular proliferation shortly after birth, followed by vascular involution in early childhood. We have found that NOTCH3, a critical regulator of mural cell differentiation and maturation, is expressed in hemangioma stem cells (He...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Edwards, Andrew K., Glithero, Kyle, Grzesik, Peter, Kitajewski, Alison A., Munabi, Naikhoba C.O., Hardy, Krista, Tan, Qian Kun, Schonning, Michael, Kangsamaksin, Thaned, Kitajewski, Jan K., Shawber, Carrie J., Wu, June K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752265/
https://ncbi.nlm.nih.gov/pubmed/29093274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.93764
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