The HLA-B*35 allele modulates ER stress, inflammation and proliferation in PBMCs from Limited Cutaneous Systemic Sclerosis patients

INTRODUCTION: HLA-B*35 is associated with increased risk of developing pulmonary hypertension in SSc patients. We previously reported that HLA-B*35 induces endothelial cell dysfunction via activation of ER stress/UPR and upregulation of the inflammatory response. Because PBMCs from lcSSc-PAH patient...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Arthritis Res Ther
Main Authors: Lenna, Stefania, Assassi, Shervin, Farina, G. Alessandra, Mantero, Julio C., Scorza, Raffaella, Lafyatis, Robert, Farber, Harrison W., Trojanowska, Maria
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704539/
https://ncbi.nlm.nih.gov/pubmed/26669670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0881-1
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker