E2F-1-mediated transactivation is inhibited by complex formation with the retinoblastoma susceptibility gene product.
Previous studies have shown that the carboxyl-terminal region of E2F-1 (residues 368-437) can support transcriptional activation when linked to the DNA-binding domain of the yeast transcription factor GAL4. This region also contains an 18-residue retinoblastoma (RB)-binding sequence, raising the pos...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1993
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47045/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8346196/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.15.6914 |
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