E2F-1-mediated transactivation is inhibited by complex formation with the retinoblastoma susceptibility gene product.

Previous studies have shown that the carboxyl-terminal region of E2F-1 (residues 368-437) can support transcriptional activation when linked to the DNA-binding domain of the yeast transcription factor GAL4. This region also contains an 18-residue retinoblastoma (RB)-binding sequence, raising the pos...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Flemington, E K, Speck, S H, Kaelin, W G
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47045/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8346196/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.15.6914
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