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A chemical–genetic interaction map of small molecules using high‐throughput imaging in cancer cells
Small molecules often affect multiple targets, elicit off‐target effects, and induce genotype‐specific responses. Chemical genetics, the mapping of the genotype dependence of a small molecule's effects across a broad spectrum of phenotypes can identify novel mechanisms of action. It can also re...
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| Udgivet i: | Mol Syst Biol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4704494/ https://ncbi.nlm.nih.gov/pubmed/26700849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20156400 |
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