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A map of directional genetic interactions in a metazoan cell

Gene–gene interactions shape complex phenotypes and modify the effects of mutations during development and disease. The effects of statistical gene–gene interactions on phenotypes have been used to assign genes to functional modules. However, directional, epistatic interactions, which reflect regula...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Fischer, Bernd, Sandmann, Thomas, Horn, Thomas, Billmann, Maximilian, Chaudhary, Varun, Huber, Wolfgang, Boutros, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4384530/
https://ncbi.nlm.nih.gov/pubmed/25748138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.05464
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