A map of directional genetic interactions in a metazoan cell

Gene–gene interactions shape complex phenotypes and modify the effects of mutations during development and disease. The effects of statistical gene–gene interactions on phenotypes have been used to assign genes to functional modules. However, directional, epistatic interactions, which reflect regula...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:eLife
Prif Awduron: Fischer, Bernd, Sandmann, Thomas, Horn, Thomas, Billmann, Maximilian, Chaudhary, Varun, Huber, Wolfgang, Boutros, Michael
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: eLife Sciences Publications, Ltd 2015
Pynciau:
Genes and Chromosomes
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4384530/
https://ncbi.nlm.nih.gov/pubmed/25748138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.05464
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