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A map of directional genetic interactions in a metazoan cell

Gene–gene interactions shape complex phenotypes and modify the effects of mutations during development and disease. The effects of statistical gene–gene interactions on phenotypes have been used to assign genes to functional modules. However, directional, epistatic interactions, which reflect regula...

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Bibliografski detalji
Izdano u:eLife
Glavni autori: Fischer, Bernd, Sandmann, Thomas, Horn, Thomas, Billmann, Maximilian, Chaudhary, Varun, Huber, Wolfgang, Boutros, Michael
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4384530/
https://ncbi.nlm.nih.gov/pubmed/25748138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.05464
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