Proteome-wide small molecule and metabolite interaction mapping

Thermal stabilization of proteins upon ligand binding provides an efficient means to assess binding of small molecules to proteins. We show here that in combination with quantitative mass spectrometry the approach allows for the systematic survey of protein engagement by cellular metabolites and dru...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Nat Methods
Asıl Yazarlar: Huber, Kilian V. M., Olek, Karin M., Müller, André C., Soon Heng Tan, Chris, Bennett, Keiryn L., Colinge, Jacques, Superti-Furga, Giulio
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4629415/
https://ncbi.nlm.nih.gov/pubmed/26389571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3590
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller