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Extracellular DNA Acidifies Biofilms and Induces Aminoglycoside Resistance in Pseudomonas aeruginosa

Biofilms consist of surface-adhered bacterial communities encased in an extracellular matrix composed of DNA, exopolysaccharides, and proteins. Extracellular DNA (eDNA) has a structural role in the formation of biofilms, can bind and shield biofilms from aminoglycosides, and induces antimicrobial pe...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Wilton, Mike, Charron-Mazenod, Laetitia, Moore, Richard, Lewenza, Shawn
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704225/
https://ncbi.nlm.nih.gov/pubmed/26552982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01650-15
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