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Extracellular DNA Shields against Aminoglycosides in Pseudomonas aeruginosa Biofilms

Within recent years, it has been established that extracellular DNA is a key constituent of the matrix of microbial biofilms. In addition, it has recently been demonstrated that DNA binds positively charged antimicrobials such as aminoglycosides and antimicrobial peptides. In the present study, we p...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chiang, Wen-Chi, Nilsson, Martin, Jensen, Peter Østrup, Høiby, Niels, Nielsen, Thomas E., Givskov, Michael, Tolker-Nielsen, Tim
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632962/
https://ncbi.nlm.nih.gov/pubmed/23478967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00001-13
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