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Extracellular DNA Chelates Cations and Induces Antibiotic Resistance in Pseudomonas aeruginosa Biofilms

Biofilms are surface-adhered bacterial communities encased in an extracellular matrix composed of DNA, bacterial polysaccharides and proteins, which are up to 1000-fold more antibiotic resistant than planktonic cultures. To date, extracellular DNA has been shown to function as a structural support t...

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Detalhes bibliográficos
Main Authors: Mulcahy, Heidi, Charron-Mazenod, Laetitia, Lewenza, Shawn
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581603/
https://ncbi.nlm.nih.gov/pubmed/19023416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000213
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