Secreted Phosphatase and Deoxyribonuclease Are Required by Pseudomonas aeruginosa To Defend against Neutrophil Extracellular Traps

Neutrophil extracellular traps (NETs) are produced by neutrophils as an innate immune defense mechanism to trap and kill microbial pathogens. NETs are comprised of ejected chromatin that forms a lattice structure enmeshed with numerous antimicrobial proteins. In addition to forming the structural ba...

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Udgivet i:Infect Immun
Main Authors: Wilton, Mike, Halverson, Tyler W. R., Charron-Mazenod, Laetitia, Parkins, Michael D., Lewenza, Shawn
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Molecular Pathogenesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6105888/
https://ncbi.nlm.nih.gov/pubmed/29967090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00403-18
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