Pharmacodynamics of Isavuconazole in a Dynamic In Vitro Model of Invasive Pulmonary Aspergillosis

Isavuconazonium sulfate is a novel triazole prodrug that has been recently approved for the treatment of invasive aspergillosis by the FDA. The active moiety (isavuconazole) has a broad spectrum of activity against many pathogenic fungi. This study utilized a dynamic in vitro model of the human alve...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Box, Helen, Livermore, Joanne, Johnson, Adam, McEntee, Laura, Felton, Timothy W., Whalley, Sarah, Goodwin, Joanne, Hope, William W.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2015
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704219/
https://ncbi.nlm.nih.gov/pubmed/26503648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01364-15
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