Pharmacodynamics of isavuconazole in experimental invasive pulmonary aspergillosis: implications for clinical breakpoints

OBJECTIVES: Isavuconazole, a novel triazole antifungal agent, has broad-spectrum activity against Aspergillus spp. and other pathogenic fungi. The isavuconazole exposure–response relationship in experimental invasive pulmonary aspergillosis using galactomannan index (GMI) suppression as a marker of...

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Detalhes bibliográficos
Publicado no:J Antimicrob Chemother
Main Authors: Kovanda, Laura L., Petraitiene, Ruta, Petraitis, Vidmantas, Walsh, Thomas J., Desai, Amit, Bonate, Peter, Hope, William W.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896411/
https://ncbi.nlm.nih.gov/pubmed/27084921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkw098
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