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Combination Therapy with Isavuconazole and Micafungin for Treatment of Experimental Invasive Pulmonary Aspergillosis

Invasive pulmonary aspergillosis (IPA) is an important cause of morbidity and mortality in immunocompromised patients. We hypothesized that simultaneous inhibition of biosynthesis of ergosterol in the fungal cell membrane and (1→3)-β-d-glucan in the cell wall, respectively, by the antifungal triazol...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Petraitis, Vidmantas, Petraitiene, Ruta, McCarthy, Matthew W., Kovanda, Laura L., Zaw, Myo H., Hussain, Kaiser, Shaikh, Naima, Maung, Bo Bo W., Sekhon, Navjot K., Hope, William W., Walsh, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571280/
https://ncbi.nlm.nih.gov/pubmed/28696236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00305-17
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