Combination Therapy with Isavuconazole and Micafungin for Treatment of Experimental Invasive Pulmonary Aspergillosis

Invasive pulmonary aspergillosis (IPA) is an important cause of morbidity and mortality in immunocompromised patients. We hypothesized that simultaneous inhibition of biosynthesis of ergosterol in the fungal cell membrane and (1→3)-β-d-glucan in the cell wall, respectively, by the antifungal triazol...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Petraitis, Vidmantas, Petraitiene, Ruta, McCarthy, Matthew W., Kovanda, Laura L., Zaw, Myo H., Hussain, Kaiser, Shaikh, Naima, Maung, Bo Bo W., Sekhon, Navjot K., Hope, William W., Walsh, Thomas J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
Témata:
Experimental Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571280/
https://ncbi.nlm.nih.gov/pubmed/28696236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00305-17
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