Pharmacodynamics of Isavuconazole in a Rabbit Model of Cryptococcal Meningoencephalitis

Cryptococcus spp., important fungal pathogens, are the leading cause of fungus-related mortality in human immunodeficiency virus-infected patients, and new therapeutic options are desperately needed. Isavuconazonium sulfate, a newer triazole antifungal agent, was studied to characterize the exposure...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Kovanda, Laura L., Giamberardino, Charles, McEntee, Laura, Toffaletti, Dena L., Franke, Kelly S., Bartuska, Andrew, Smilnak, Gordon, de Castro, George C., Ripple, Katelyn, Hope, William W., Perfect, John R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2019
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6709487/
https://ncbi.nlm.nih.gov/pubmed/31209006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00546-19
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