No Need for Lopinavir Dose Adjustment during Pregnancy: a Population Pharmacokinetic and Exposure-Response Analysis in Pregnant and Nonpregnant HIV-Infected Subjects

Lopinavir-ritonavir is frequently prescribed to HIV-1-infected women during pregnancy. Decreased lopinavir exposure has been reported during pregnancy, but the clinical significance of this reduction is uncertain. This analysis aimed to evaluate the need for lopinavir dose adjustment during pregnanc...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Antimicrob Agents Chemother
Prif Awduron: Salem, Ahmed Hamed, Jones, Aksana Kaefer, Santini-Oliveira, Marilia, Taylor, Graham P., Patterson, Kristine B., Nilius, Angela M., Klein, Cheri Enders
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2015
Pynciau:
Antiviral Agents
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704200/
https://ncbi.nlm.nih.gov/pubmed/26525798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01197-15
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