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Dose Separation Does Not Overcome the Pharmacokinetic Interaction between Fosamprenavir and Lopinavir/Ritonavir

Previous investigations have shown a significant negative two-way drug interaction between fosamprenavir (FPV) and lopinavir/ritonavir (LPV/RTV) in both human immunodeficiency virus (HIV)-infected patients and seronegative volunteers. This randomized, nonblinded, three-way crossover study of HIV-ser...

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Detalhes bibliográficos
Main Authors: Corbett, Amanda H., Patterson, Kristine B., Tien, Hsiao-Chuan, Kalvass, Leslie A., Eron, Joseph J., Ngo, Linh T., Lim, Michael L., Kashuba, Angela D. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1538690/
https://ncbi.nlm.nih.gov/pubmed/16870769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01006-05
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