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Kinetics of nucleotide-dependent structural transitions in the kinesin-1 hydrolysis cycle
To dissect the kinetics of structural transitions underlying the stepping cycle of kinesin-1 at physiological ATP, we used interferometric scattering microscopy to track the position of gold nanoparticles attached to individual motor domains in processively stepping dimers. Labeled heads resided sta...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4702989/ https://ncbi.nlm.nih.gov/pubmed/26676576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1517638112 |
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