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Ezh2 regulates differentiation and function of natural killer cells through histone methyltransferase activity

Changes of histone modification status at critical lineage-specifying gene loci in multipotent precursors can influence cell fate commitment. The contribution of these epigenetic mechanisms to natural killer (NK) cell lineage determination from common lymphoid precursors is not understood. Here we i...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Yin, Jie, Leavenworth, Jianmei W., Li, Yang, Luo, Qi, Xie, Huafeng, Liu, Xinhua, Huang, Shan, Yan, Han, Fu, Zheng, Zhang, Liyun Y., Zhang, Litao, Hao, Junwei, Wu, Xudong, Deng, Xianming, Roberts, Charles W. M., Orkin, Stuart H., Cantor, Harvey, Wang, Xi
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702963/
https://ncbi.nlm.nih.gov/pubmed/26668377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1521740112
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