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Ezh2 regulates differentiation and function of natural killer cells through histone methyltransferase activity
Changes of histone modification status at critical lineage-specifying gene loci in multipotent precursors can influence cell fate commitment. The contribution of these epigenetic mechanisms to natural killer (NK) cell lineage determination from common lymphoid precursors is not understood. Here we i...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4702963/ https://ncbi.nlm.nih.gov/pubmed/26668377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1521740112 |
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