Ezh2 regulates differentiation and function of natural killer cells through histone methyltransferase activity

Changes of histone modification status at critical lineage-specifying gene loci in multipotent precursors can influence cell fate commitment. The contribution of these epigenetic mechanisms to natural killer (NK) cell lineage determination from common lymphoid precursors is not understood. Here we i...

詳細記述

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Yin, Jie, Leavenworth, Jianmei W., Li, Yang, Luo, Qi, Xie, Huafeng, Liu, Xinhua, Huang, Shan, Yan, Han, Fu, Zheng, Zhang, Liyun Y., Zhang, Litao, Hao, Junwei, Wu, Xudong, Deng, Xianming, Roberts, Charles W. M., Orkin, Stuart H., Cantor, Harvey, Wang, Xi
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2015
主題:
Biological Sciences
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702963/
https://ncbi.nlm.nih.gov/pubmed/26668377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1521740112
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