Prion Type-Dependent Deposition of PRNP Allelic Products in Heterozygous Sheep

Susceptibility or resistance to prion infection in humans and animals depends on single prion protein (PrP) amino acid substitutions in the host, but the agent's modulating role has not been well investigated. Compared to disease incubation times in wild-type homozygous ARQ/ARQ (where each trip...

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Udgivet i:J Virol
Main Authors: Langeveld, J. P. M., Jacobs, J. G., Hunter, N., van Keulen, L. J. M., Lantier, F., van Zijderveld, F. G., Bossers, A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Prions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702698/
https://ncbi.nlm.nih.gov/pubmed/26512080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02316-15
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