Proteinase K-Resistant Material in ARR/VRQ Sheep Brain Affected with Classical Scrapie Is Composed Mainly of VRQ Prion Protein

Classical scrapie is a prion disease in sheep and goats. In sheep, susceptibility to disease is genetically influenced by single amino acid substitutions. Genetic breeding programs aimed at enrichment of arginine-171 (171R) prion protein (PrP), the so-called ARR allele, in the sheep population have...

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Detalhes bibliográficos
Main Authors: Jacobs, J. G., Bossers, A., Rezaei, H., van Keulen, L. J. M., McCutcheon, S., Sklaviadis, T., Lantier, I., Berthon, P., Lantier, F., van Zijderveld, F. G., Langeveld, J. P. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Structure and Assembly
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209378/
https://ncbi.nlm.nih.gov/pubmed/21917981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00448-11
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