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The Oral Secretion of Infectious Scrapie Prions Occurs in Preclinical Sheep with a Range of PRNP Genotypes

Preclinical sheep with the highly scrapie-susceptible VRQ/VRQ PRNP genotype secrete prions from the oral cavity. In order to further understand the significance of orally available prions, buccal swabs were taken from sheep with a range of PRNP genotypes and analyzed by serial protein misfolding cyc...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Gough, Kevin C., Baker, Claire A., Rees, Helen C., Terry, Linda A., Spiropoulos, John, Thorne, Leigh, Maddison, Ben C.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255911/
https://ncbi.nlm.nih.gov/pubmed/22013047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05579-11
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