Environmental Sources of Scrapie Prions

Ovine scrapie and cervine chronic wasting disease show considerable horizontal transmission. Here we report that a scrapie-affected sheep farm has a widespread environmental contamination with prions. Prions were amplified by protein-misfolding cyclic amplification (sPMCA) from seven of nine environ...

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Bibliographische Detailangaben
Hauptverfasser: Maddison, Ben C., Baker, Claire A., Terry, Linda A., Bellworthy, Susan J., Thorne, Leigh, Rees, Helen C., Gough, Kevin C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953180/
https://ncbi.nlm.nih.gov/pubmed/20739536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01133-10
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