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Ebolavirus Glycoprotein Directs Fusion through NPC1(+) Endolysosomes

Ebolavirus, a deadly hemorrhagic fever virus, was thought to enter cells through endolysosomes harboring its glycoprotein receptor, Niemann-Pick C1. However, an alternate model was recently proposed in which ebolavirus enters through a later NPC1-negative endosome that contains two-pore Ca(2+) chann...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Simmons, James A., D'Souza, Ryan S., Ruas, Margarida, Galione, Antony, Casanova, James E., White, Judith M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702577/
https://ncbi.nlm.nih.gov/pubmed/26468524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01828-15
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