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The Primed Ebolavirus Glycoprotein (19-Kilodalton GP(1,2)): Sequence and Residues Critical for Host Cell Binding

Entry of ebolavirus (EBOV) into cells is mediated by its glycoprotein (GP(1,2)), a class I fusion protein whose structure was recently determined (J. E. Lee et al., Nature 454:177-182, 2008). Here we confirmed two major predictions of the structural analysis, namely, the residues in GP(1) and GP(2)...

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Autors principals: Dube, Derek, Brecher, Matthew B., Delos, Sue E., Rose, Sean C., Park, Edward W., Schornberg, Kathryn L., Kuhn, Jens H., White, Judith M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655554/
https://ncbi.nlm.nih.gov/pubmed/19144707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01956-08
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