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Ebolavirus Entry Requires a Compact Hydrophobic Fist at the Tip of the Fusion Loop

Ebolavirus is an enveloped virus causing severe hemorrhagic fever. Its surface glycoproteins undergo proteolytic cleavage and rearrangements to permit membrane fusion and cell entry. Here we focus on the glycoprotein's internal fusion loop (FL), critical for low-pH-triggered fusion in the endos...

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Autors principals: Gregory, Sonia M., Larsson, Per, Nelson, Elizabeth A., Kasson, Peter M., White, Judith M., Tamm, Lukas K.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054381/
https://ncbi.nlm.nih.gov/pubmed/24696482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00396-14
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