Ebolavirus Entry Requires a Compact Hydrophobic Fist at the Tip of the Fusion Loop

Ebolavirus is an enveloped virus causing severe hemorrhagic fever. Its surface glycoproteins undergo proteolytic cleavage and rearrangements to permit membrane fusion and cell entry. Here we focus on the glycoprotein's internal fusion loop (FL), critical for low-pH-triggered fusion in the endos...

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Autores principales: Gregory, Sonia M., Larsson, Per, Nelson, Elizabeth A., Kasson, Peter M., White, Judith M., Tamm, Lukas K.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2014
Materias:
Virus-Cell Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054381/
https://ncbi.nlm.nih.gov/pubmed/24696482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00396-14
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