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Immune homeostasis enforced by co-localized effector and regulatory T cells

Foxp3(+) regulatory T cells (Tregs) play a critical role in preventing autoimmune disease by limiting the effector activity of conventional T cells that have escaped thymic negative selection or cell-autonomous peripheral inactivation(1–3). However, despite the substantial information available abou...

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Detalles Bibliográficos
Publicado en:Nature
Main Authors: Liu, Zhiduo, Gerner, Michael Y., Van Panhuys, Nicholas, Levine, Andrew G., Rudensky, Alexander Y., Germain, Ronald N.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702500/
https://ncbi.nlm.nih.gov/pubmed/26605524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature16169
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