Allergen-induced CD4(+) T-cell cytokine production within airway mucosal DC-T-cell clusters drives the local recruitment of myeloid effector cells()

Allergic asthma develops in the mucosal tissue of small bronchi. At these sites, local cytokine production by T(H)2/T(H)17 cells is believed to be critical for the development of tissue eosinophilia/neutrophilia. Using the mouse trachea as a relevant model of human small airways, we performed advanc...

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Bibliografiske detaljer
Udgivet i:	J Immunol
Main Authors:	Veres, Tibor Z., Kopcsányi, Tamás, van Panhuys, Nicholas, Gerner, Michael Y., Liu, Zhiduo, Rantakari, Pia, Dunkel, Johannes, Miyasaka, Masayuki, Salmi, Marko, Jalkanen, Sirpa, Germain, Ronald N.
Format:	Artigo
Sprog:	Inglês
Udgivet:	2016
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC5225021/ https://ncbi.nlm.nih.gov/pubmed/27903737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601448
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Allergen-induced CD4(+) T-cell cytokine production within airway mucosal DC-T-cell clusters drives the local recruitment of myeloid effector cells()

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