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Allergen-induced CD4(+) T-cell cytokine production within airway mucosal DC-T-cell clusters drives the local recruitment of myeloid effector cells()
Allergic asthma develops in the mucosal tissue of small bronchi. At these sites, local cytokine production by T(H)2/T(H)17 cells is believed to be critical for the development of tissue eosinophilia/neutrophilia. Using the mouse trachea as a relevant model of human small airways, we performed advanc...
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| Pubblicato in: | J Immunol |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5225021/ https://ncbi.nlm.nih.gov/pubmed/27903737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601448 |
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