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Immune homeostasis enforced by co-localized effector and regulatory T cells
Foxp3(+) regulatory T cells (Tregs) play a critical role in preventing autoimmune disease by limiting the effector activity of conventional T cells that have escaped thymic negative selection or cell-autonomous peripheral inactivation(1–3). However, despite the substantial information available abou...
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| Veröffentlicht in: | Nature |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4702500/ https://ncbi.nlm.nih.gov/pubmed/26605524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature16169 |
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