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Identification and classification of small molecule kinases: insights into substrate recognition and specificity
BACKGROUND: Many prokaryotic kinases that phosphorylate small molecule substrates, such as antibiotics, lipids and sugars, are evolutionarily related to Eukaryotic Protein Kinases (EPKs). These Eukaryotic-Like Kinases (ELKs) share the same overall structural fold as EPKs, but differ in their modes o...
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Publicado no: | BMC Evol Biol |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4702295/ https://ncbi.nlm.nih.gov/pubmed/26738562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12862-015-0576-x |
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