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Modeling the evolution space of breakage fusion bridge cycles with a stochastic folding process
Breakage–fusion–bridge cycles in cancer arise when a broken segment of DNA is duplicated and an end from each copy joined together. This structure then ‘unfolds’ into a new piece of palindromic DNA. This is one mechanism responsible for the localised amplicons observed in cancer genome data. Here we...
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| Publicado no: | J Math Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4702116/ https://ncbi.nlm.nih.gov/pubmed/25833184 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00285-015-0875-2 |
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