MicroRNA-31 initiates lung tumorigenesis and promotes mutant KRAS-driven lung cancer

MicroRNA (miR) are important regulators of gene expression, and aberrant miR expression has been linked to oncogenesis; however, little is understood about their contribution to lung tumorigenesis. Here, we determined that miR-31 is overexpressed in human lung adenocarcinoma and this overexpression...

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Vydáno v:J Clin Invest
Hlavní autoři: Edmonds, Mick D., Boyd, Kelli L., Moyo, Tamara, Mitra, Ramkrishna, Duszynski, Robert, Arrate, Maria Pia, Chen, Xi, Zhao, Zhongming, Blackwell, Timothy S., Andl, Thomas, Eischen, Christine M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701567/
https://ncbi.nlm.nih.gov/pubmed/26657862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI82720
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