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The ERBB network facilitates KRAS-driven lung tumorigenesis
KRAS is the most frequently mutated driver oncogene in human adenocarcinoma of the lung. There are presently no clinically proven strategies for treatment of KRAS-driven lung cancer. Activating mutations in KRAS are thought to confer independence from upstream signaling, however recent data suggest...
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| Gepubliceerd in: | Sci Transl Med |
|---|---|
| Hoofdauteurs: | , , , , , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6881183/ https://ncbi.nlm.nih.gov/pubmed/29925636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aao2565 |
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