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Mycobacterium tuberculosis oriC sequestration by MtrA response regulator

The regulators of Mycobacterium tuberculosis DNA replication are largely unknown. Here, we demonstrate that in synchronously replicating M. tuberculosis, MtrA access to origin of replication (oriC) is enriched in the post-replication (D) period. The increased oriC binding results from elevated MtrA...

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Detalles Bibliográficos
Publicado en:Mol Microbiol
Main Authors: Purushotham, Gorla, Sarva, Krishna B., Blaszczyk, Ewelina, Rajagopalan, Malini, Madiraju, Murty V.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4700885/
https://ncbi.nlm.nih.gov/pubmed/26207528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13144
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