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Mycobacterium tuberculosis mtrA merodiploid strains with point mutations in the signal-receiving domain of MtrA exhibit growth defects in nutrient broth

The genetic and biochemical aspects of the essential Mycobacterium tuberculosis MtrAB two-component regulatory signal transduction (2CRS) system have not been extensively investigated. We show by bacterial two-hybrid assay that the response regulator (RR) MtrA and the sensor kinase MtrB interact. We...

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Detalhes bibliográficos
Main Authors: Zayer, Maha Al, Stankowska, Dorota, Dziedzic, Renata, Sarva, Krishna, Madiraju, Murty V., Rajagopalan, Malini
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076548/
https://ncbi.nlm.nih.gov/pubmed/21295603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.plasmid.2011.01.002
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