MtrA Response Regulator Controls Cell Division and Cell Wall Metabolism and Affects Susceptibility of Mycobacteria to the First Line Antituberculosis Drugs

The biological processes regulated by the essential response regulator MtrA and the growth conditions promoting its activation in Mycobacterium tuberculosis, a slow grower and pathogen, are largely unknown. Here, using a gain-of-function mutant, MtrA(Y 102C), which functions in the absence of the co...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Gorla, Purushotham, Plocinska, Renata, Sarva, Krishna, Satsangi, Akash T., Pandeeti, Emmanuel, Donnelly, Robert, Dziadek, Jaroslaw, Rajagopalan, Malini, Madiraju, Murty V.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6265350/
https://ncbi.nlm.nih.gov/pubmed/30532747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.02839
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