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HIV-1 latency and virus production from unintegrated genomes following direct infection of resting CD4 T cells
BACKGROUND: HIV-1 integration is prone to a high rate of failure, resulting in the accumulation of unintegrated viral genomes (uDNA) in vivo and in vitro. uDNA can be transcriptionally active, and circularized uDNA genomes are biochemically stable in non-proliferating cells. Resting, non-proliferati...
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| 出版年: | Retrovirology |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4700562/ https://ncbi.nlm.nih.gov/pubmed/26728316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-015-0234-9 |
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