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HIV-1 Vpr- and Reverse Transcription-Induced Apoptosis in Resting Peripheral Blood CD4 T Cells and Protection by Common Gamma-Chain Cytokines

HIV-1 infection leads to the progressive depletion of the CD4 T cell compartment by various known and unknown mechanisms. In vivo, HIV-1 infects both activated and resting CD4 T cells, but in vitro, in the absence of any stimuli, resting CD4 T cells from peripheral blood are resistant to infection....

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Podrobná bibliografie
Vydáno v:J Virol
Hlavní autoři: Trinité, Benjamin, Chan, Chi N., Lee, Caroline S., Levy, David N.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702666/
https://ncbi.nlm.nih.gov/pubmed/26537673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01770-15
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