Messenger RNA delivery of a cartilage-anabolic transcription factor as a disease-modifying strategy for osteoarthritis treatment

Osteoarthritis (OA) is a chronic degenerative joint disease and a major health problem in the elderly population. No disease-modifying osteoarthritis drug (DMOAD) has been made available for clinical use. Here we present a disease-modifying strategy for OA, focusing on messenger RNA (mRNA) delivery...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Aini, Hailati, Itaka, Keiji, Fujisawa, Ayano, Uchida, Hirokuni, Uchida, Satoshi, Fukushima, Shigeto, Kataoka, Kazunori, Saito, Taku, Chung, Ung-il, Ohba, Shinsuke
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4700530/
https://ncbi.nlm.nih.gov/pubmed/26728350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18743
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