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Messenger RNA-based therapeutics for the treatment of apoptosis-associated diseases

Gene therapy is a promising approach for treating diseases that are closely associated with excessive apoptosis, because the gene can effectively and sustainably introduce anti-apoptotic factors into cells. However, DNA delivery poses the risk of random genomic integration, leading to overexpression...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Matsui, Akitsugu, Uchida, Satoshi, Ishii, Takehiko, Itaka, Keiji, Kataoka, Kazunori
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623474/
https://ncbi.nlm.nih.gov/pubmed/26507781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15810
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