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Treatment of Intervertebral Disk Disease by the Administration of mRNA Encoding a Cartilage-Anabolic Transcription Factor

Intervertebral disk (IVD) degeneration is often associated with severity of lower back pain. IVD core is an avascular, highly hydrated tissue composed of type II collagen, glycosaminoglycans, and proteoglycans. The disk degeneration is not only a destruction of IVD structure but also is related to a...

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Vydáno v:Mol Ther Nucleic Acids
Hlavní autoři: Lin, Chin-Yu, Crowley, Samuel Thomas, Uchida, Satoshi, Komaki, Yuji, Kataoka, Kazunori, Itaka, Keiji
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Gene & Cell Therapy 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6424144/
https://ncbi.nlm.nih.gov/pubmed/30889482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.02.012
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