Renal Ischemia/Reperfusion Injury in Soluble Epoxide Hydrolase-Deficient Mice

AIM: 20-hydroxyeicosatetraenoic acid (20-HETE) and epoxyeicosatrienoic acids (EETs) are cytochrome P450 (CYP)-dependent eicosanoids that play opposite roles in the regulation of vascular tone, inflammation, and apoptosis. 20-HETE aggravates, whereas EETs ameliorate ischemia/reperfusion (I/R)-induced...

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發表在:PLoS One
Main Authors: Zhu, Ye, Blum, Maximilian, Hoff, Uwe, Wesser, Tim, Fechner, Mandy, Westphal, Christina, Gürgen, Dennis, Catar, Rusan Ali, Philippe, Aurelie, Wu, Kaiyin, Bubalo, Gordana, Rothe, Michael, Weldon, Steven M., Dragun, Duska, Schunck, Wolf-Hagen
格式: Artigo
語言:Inglês
出版: Public Library of Science 2016
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4699807/
https://ncbi.nlm.nih.gov/pubmed/26727266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145645
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