A SYNTHETIC EPOXYEICOSATRIENOIC ACID ANALOG PREVENTS THE INITIATION OF ISCHEMIC ACUTE KIDNEY INJURY

AIM: Imbalances in cytochrome P450 (CYP)-dependent eicosanoid formation may play a central role in ischemic acute kidney injury (AKI). We reported previously that inhibition of 20-hydroxyeicosatetraenoic acid (20-HETE) action ameliorated ischemia/reperfusion (I/R)-induced AKI in rats. Now we tested...

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Udgivet i:Acta Physiol (Oxf)
Main Authors: Hoff, Uwe, Bubalo, Gordana, Fechner, Mandy, Blum, Maximilian, Zhu, Ye, Pohlmann, Andreas, Hentschel, Jan, Arakelyan, Karen, Seeliger, Erdmann, Flemming, Bert, Gürgen, Dennis, Rothe, Michael, Niendorf, Thoralf, Manthati, Vijaya L., Falck, John R., Haase, Michael, Schunck, Wolf-Hagen, Dragun, Duska
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6733619/
https://ncbi.nlm.nih.gov/pubmed/31077555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/apha.13297
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